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Image Search Results
Journal: CPT: Pharmacometrics & Systems Pharmacology
Article Title: A PBPK Model to Predict Disposition of CYP3A-Metabolized Drugs in Pregnant Women: Verification and Discerning the Site of CYP3A Induction
doi: 10.1038/psp.2012.2
Figure Lengend Snippet: A schematic representation of the pregnancy physiologically based pharmacokinetic model (PBPK) model. The PBPK model is an extension of the Simcyp 13-compartment full-PBPK model, and includes a lumped compartment to represent placental–fetal organs including the fetus, placenta, and the amniotic fluid. Reproduced from Lu et al. 2012.
Article Snippet: Briefly, the PBPK model is an extension of the
Techniques: